Tuesday, December 24, 2019

My Experience At The Whelchel Family Life Center - 1698 Words

Introduction There is always more than one way to do something and education is no exception. Educators have different philosophies and classroom approaches depending on their subject and the type of students that they have. This semester, I had the opportunity to apply information from a class to real world situations. Through my field experience at the Whelchel Family Life Center, I was able to see the challenges associated with teaching different social classes, different demographics, and different learning styles. I was able to learn how to navigate through common challenges from observing my mentoring instructors, which in turn will help me to develop my own teaching style and better prepare me to be a future educator. Whelchel Family Life Center The Whelchel Family Life Center is a non-profit center whose goal is â€Å"to provide services to the community by enriching the spiritual, educational, physical, emotional, and social needs of youth, elderly, and families of the local and surrounding communities† (W.L.). This center is used to promote health for all members of the community in need of support mentally or physically. I worked closely first through eighth graders. There was a variety of both male and female students. The demographics was mostly African American students and mentors, but some Caucasian students and volunteers. Most of the children did not suffer from any learning disabilities and readily absorbed information in the classroom. Because of the age

Monday, December 16, 2019

Travel Brochure Free Essays

The Pharaohs were the most powerful and the most important people in the kingdom. He ruled the government, the military, the religion and all his people. They were the kings and queens of Egypt. We will write a custom essay sample on Travel Brochure or any similar topic only for you Order Now Many people also believed that pharaohs were half god. They believed the Pharaoh was the sun god Re. Pharaohs also often had many wives but they only had one queen. The Great Pyramids of Giza- There are 3 chambers inside the pyramid. The lower one, is made of limestone bedrock and was never completed. The 2nd and 3rd were known as the king and queens chamber. Surrounding the pyramid are tombs, statues, and other monuments, this certainly would be a site to see! Step Pyramid at Saqqara- This was the 1st stone building ever made. Djoser constructed this beauty. Where will we be traveling? And who are the Pharaohs. Delete box or place a tag line or quote here. Delete box or place a tag line or quote here. 5555 Street Address City, State 55555 Telephone 555. 555. 5555 Facsimile 555. 555. 5555 DELETE BOX, OR PLACE TEXT OR LOGO HERE www. webaddress. com During the 2nd half of the old kingdom Saqqara was known as the royal burying grounds. The step pyramid of djoser was created all out of stone. It’s also often referred to (because of its rectangular base) as the Step Tomb. Its surrounded by ceremonial structures as well as many decorations. When Djoser led, he led his people through time of advancements and expansion. To expand Egypt’s territory, he fought foreign invaders on both the eastern and western sides. When Djoser ruled he also ended the famine that had been bringing down his empire. Before Djoser’s time there was a lot of hardship, but he got people back on track and his efforts also lead to more agriculture and farming. He was a wonderful and respected leader. Leader- Djoser Karnak SUBHEAD Delete box or place a tag line or quote here. Delete box or place a tag line or quote here. * HEADLINE Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Continue brochure text here. Saqqara t How to cite Travel Brochure, Papers

Sunday, December 8, 2019

Laura Ashley Holdings the Battle for Survival free essay sample

Laura Ashley Holdings: The Battle for Survival 1. Assess the company’s recent performance. How serious is the company’s present predicament? Laura Ashley’s business performance has been on the decline since the early 1990’s. Although with the numerous changes of CEO’s, including the highly paid turnaround executive Ann Iverson, Laura Ashley is still left far behind the competitors and unable to keep up with the growth of economy. Laura Ashley’s decline of business performance can be observed from the following: †¢Financials: sales have declined from 1995 to 1999, with the North America Region being the most noticeable: over 40% of decrease in five years. Profits have peaked near the mid-90 but decreased overall since the early 90’s. Deficits occurred nearly every year, especially negative cash flow, leaving decreased return for the stockholders and requiring even more to fund continuing operations. More capital has been raised by the issuance of stocks, partially used to buy back debt to relief interest expenses and retain relationships with financial institutions; rest goes toward the closure of stores and expenses of restructure, which has yet been proven effective. Stock prices have fallen to an all time low in 1998. †¢Shortage of financing: banks have demanded Laura Ashley to decrease its debt and seem to be reluctant in lending more funds, just to see it getting drained by the continuing negative cash flows. Company currently only has one major source of funding, MUI, which owns 40% of Laura Ashley’s stocks, and its willingness to invest further is questionable since ? 43. 5 million of investment only resulted in a deficit in 1999. †¢Expansion vs. retrenchment: one of Iverson’s turnaround strategies is to rid the small, unprofitable stores, and open new, larger stores that are supposedly more potentially profitable. Floor space has increased since the mid-90 but number of stores has decreased. According to the financial data, the company has sold more than 60% of its assets since 1989. Disintegrating of operations has begun as manufacturing operations have been sold with a continuing supply agreement. †¢Competitiveness: Laura Ashley’s sales data is toward the very bottom of industry range, less than a quarter of Next plc. The margins and turnover ratios are lower than the industry average, with profit margin and ROE in the negatives. 2. Using the data available, what reasons for the deteriorating performance can you identify? The following factors resulted in the decreased performance assessed above: Environment/industry: Laura Ashley has truly outgrown itself. The once successful UK Company that only specialized in home decor is now trying to tap in the garment design, expend every line of selection, and rapidly grow internationally, especially in North America where the company does not have a good understanding of the market place. Laura Ashley’s operations is highly vertically integrated, covering design, manufacturing, distribution and retai ling in 13 countries, making the overhead costs extremely high and leaving almost no exit strategy. The recent CEO’s have tried fewer but larger stores, but as noted by David Hoare, still doesn’t seem to be successful, mainly due to inadequate supply chain, raising costs of rents and halted sales growth. †¢Positioning: Laura Ashley used thrive upon the traditional, county style to target middle to older aged women, and the strategy has been proven successful. Recently, with the international expansions, the new designers tried to capture the market of younger women. However, according to the case, it has failed to consolidate any significant, new customers, while losing older customers. Laura Ashley used to use purely full, value-based pricing strategy, but decided to go with more markdowns at the end of the seasons, destroying the image of the company as a high-end decor/fashion manufacturer. †¢Decentralized organization: ever since the rapid expansion in the early 90’s, Laura Ashley’s management seem to be very decentralized, even with separate mail order catalogs for each sales region. Recently the higher evel management team has been restructured, but still doesn’t seem to be effective. 3. What strategy recommendations would you offer to Mr. Cheong that would best serve the interests of Laura Ashley’s shareholders? †¢Reposition and refocus: the designing focus should roll back to the traditional country style that people loved, mainly home decor, which is the specialty of Laura Ashley. The company needs to consolidate the past and existing customers: middle to older aged women, and will benefit from the aging world population. Clothing merchandise should be supporting, not overwhelming the home decor lines. Laura Ashley should also reposition itself as the UK based, high-end home decor designer, and classy imports to other countries, not domesticated products with retail stores all around the world. This reposition leads to the following: †¢Retrenchment: not every product has a large enough audience to support the entire world, especially traditional British country style decor, which may not be perceived as stylish in Asian countries. Instead of the gigantic overhead incurred by opening retail stores, Laura Ashley should close down most of the smaller retail stores and stop franchising activities, retrenching to become once again UK-exclusive, and open a few high-end, large showrooms in key locations around the world, such as New York, LA, Tokyo, and Beijing to promote the brand. This strategy coincides with the recent sale of manufacturing operations since sales will decrease, but as operating costs decrease, income should once again become positive. International sales should be handled by using e-commerce and special ordering from the showrooms and affiliates. E-commerce: with Amazon. com becoming profitable and the huge success of eBay, many companies started to reposition their focus on e-commerce, such as Sears Holdings, who exited the mail ordering business in the late 90’s and now does over 10% of sales online. Laura Ashley needs to develop an e-commerce model with websites, wide selections, solid c ustomer service and a convenient transportation method to let customers enjoy the same experience as shopping at a retail store. E-commerce has been proven cost-effective as it is relatively low cost, easy maintenance, and has an unlimited target audience of the whole world.

Saturday, November 30, 2019

The Spider free essay sample

This essay looks at how two poets utilize a spider in their poems for completely different purposes in Frosts Design and Whitmans Noiseless Patient Spider. This essay contrasts how poets, Robert Frost and Walt Whitman, both eloquently utilize a minute spider and turn this creature of nature into a grandiose display of life, but for opposite reasons. The author shows how Frost?s spider is a mediation of mans attempts and failures in finding order and meaning in the universe, whereas, Whitmans is a contemplation of mans attempt to fully connect to and understand the world around him. From the paper: ?Poems, unlike prose, are direct expressions of a creators feelings. Though a poet also makes use of metaphors and figurative speech to convey images, it is something else beyond the upper layer of language that makes a poem work. It is something that relates directly to the feelings and passions of the poet. We will write a custom essay sample on The Spider or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page For example, Robert Frosts poem, Design, is an exquisite play on striking images of dark and light, offering a look into this oppressive and isolated poets stark outlook on life. Whereas, his comrade, Walt Whitman, goes far above and beyond in both voice and metrical line with such a striking mural expansion of his optimistic view of the world around him in his poem, Noiseless, Patient Spider.

Tuesday, November 26, 2019

Understand the French Expression En Retard

Understand the French Expression En Retard The French expression en retard (pronounced [a(n) reu tar]) can be translated by late or any number of synonyms: behind, overdue, delayed, etc. En retard is adverbial, meaning that it must be used with a verb, usually à ªtre or arriver. Note that the French translation of late as an adjective (to be used  with  a noun) is  tardif. For example,  un  repas  tardif   a late meal. Examples Tu es en retard !Youre late!Je suis en retard mon rendez-vous.Im late for my appointment.Il va arriver en retard ce matin.Hell be (arriving) late this morning.Elle est arrivà © en retard au travail.She was late for work. (Note that the offensive English word retard is a faux ami.) Expressions with retard avoir du retardto be (running) late, to be overdueavoir (une heure, trois semaines...) de retardto be (an hour, three weeks...) lateà ªtre en retard pour son à ¢geto be backward for ones ageà ªtre en retard sur lhoraire / le programmeto be behind scheduleà ªtre en retard sur son temps / sià ¨cleto be behind the timesmettre (quelquun) en retardto make (someone) late(le courrier / travail) en retardbacklog (of mail / work) Antonym en avanceearly, ahead of schedule

Friday, November 22, 2019

The Winning Formula for Writing Success

The Winning Formula for Writing Success The Winning Formula for Writing Success The Winning Formula for Writing Success By Mark Nichol When I wrote the heading for today’s post, I thought to myself, â€Å"I should be making infomercials and workshop presentations, offering my ‘secret’ for a thousand dollars.† A thousand dollars a head for even a few dozen participants? That’s what I call successful writing: With one phrase and a few platitudes, I could take a couple of years off from work. Nah. I’ll give it to you free of charge: Quality requires quantity. Yes? And? That’s it. Quality requires quantity. Oh, all right. I’ll expound. That’s a layered statement, one that’s as deep as you want to dive. But on its most basic level, it means that an output of high quality must be preceded by an input of high quantity. In other words, a return of quality takes an investment of quantity. The new publishing model is that, thanks to the Internet, everyone’s a writer. That’s the good news. But it’s also the bad news, because it means that because many writers in this suddenly expanded universe are not highly qualified, the universe is degraded. There have always been less-than-stellar writers, but it was more difficult for them to publish their work and sustain success. Now, however, nonprofessional writers can be forgiven for believing that because it’s easy to type, it’s easy to write. And the remaining exemplars of great writing are lost in the leveling of the signal-to-noise ratio if they are sought out at all anymore. The brave new world of formal publishing is also degraded, in this case by a business model that no longer values quality because remember, quality requires quantity (and quantity, of course, requires financial investment). So now, I can find six typographical errors stuffed into a twenty-word caption in the website for a major metropolitan newspaper (since corrected because, hey, it’s the instant Internet, and we can always fix it later!), and I can find my enjoyment of a newly published book compromised by shoddy editing (improvement of which must wait for the second edition, if there is one, and if there is the wherewithal to improve it but that’s too late for me). That’s why I may come across as a dinosaur about these things, because I believe that if something is worth doing, it is worth doing well. And because I believe that, that’s why I’m proud to remain part of the old-school old guard, editing book manuscripts for publishers willing to spend time, effort, and especially money to ensure that their products reflect their high standards. Quality requires quantity. Oh, quality is sometimes accidentally produced with a minimum of quantity, but standards cannot rely on serendipity. The work ethic is called that for a reason: Good isn’t easy. It takes effort. Quality requires quantity. There’s at least one other layer to the formula. Last week, I wrote a post about another formula, what I call a writing-competence matrix. Rather than explain it here, I invite you to read the post, if you haven’t already, or to review it, if you have. Go ahead. I’ll wait. What does it take to score high on this matrix? Don’t expect to ever hit â€Å"Expert† on all three counts; many successful writers may excel in only one category. But to rate highly in even one area takes time. Remember the 10,000-Hour Rule? (That’s all right. I’ll still be here when you get back.) If you want to be a great writer, be content at first with endeavoring to be a good writer. Great can wait. But to become a good writer, you must invest quantity in your quest for quality quantity of time and effort. And you must be willing to labor not only longitudinally, putting in years of skill development, but also latitudinally, massaging, refining, and polishing each piece of writing along the way. Remember this truism: If it’s easy, you’re probably not doing it right. Quality requires quantity. Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Writing Basics category, check our popular posts, or choose a related post below:75 Synonyms for â€Å"Angry†Do you "orient" yourself, or "orientate" yourself?Is "Number" Singular or Plural?

Thursday, November 21, 2019

ESD ( Emergency shout down) tool (chemical engneering) Essay

ESD ( Emergency shout down) tool (chemical engneering) - Essay Example With all the components functioning properly, ESD can process an incoming input from the sensors and sends an output signal to initiate a response that handles the emergency. The principle parts of the system are the sensors, valves actuators and the logics units. When an output signal is sent to the valve in the event of any risk, a solenoid valves responds by initiating failure response and the programmed logical action is carried out. An impedance device with direct current power system boosts the solenoid operations, the power also runs the processor, but it has to be converted back to alternating current. In most cases, emergency tools or devices are used to perform safety operations, which includes shutting down an equipment or process when a fault is detect, such faults includes damage to the system or improper operation that can lead to damages. In some cases, emergency shutdown system can isolate a part of a system that may be presenting some risks such as deactivating hydrocarbon inventories, stopping hydrocarbon flow and depressurizing the system. ESD gives the operator a variety of integration options; one can integrate it as a stand-alone or full integration courtesy of its unique circuit design. It has a fully loaded library with operative commands that includes graphics, trend extended automation entities such as faceplates, graphic elements, trends, document links and alarms and events. In addition, ABB provides a broad family of industry-specific libraries that contain Control Modules, Function Blocks, Data Types and graphic elements including special safety systems features for ESD applications1. These pre-tested and safety-certified libraries significantly reduce the time required to engineer, test and maintain control while minimizing project risks. These libraries are certified for Safety Integrity Levels 3 and 2. The visualization system can be designed specifically fit the

Tuesday, November 19, 2019

Case study Essay Example | Topics and Well Written Essays - 2750 words - 4

Case study - Essay Example Through this program, company collected the discarded systems waste from the customers and delivered it to the certified vendors. The vendors were certified by the Pollution Control Board. In 2007, Wipro also appeared as a first Indian company which introduced eco-friendly range of desktops and laptops. By introducing these laptops and desktops, Wipro was aiming to reduce e-waste in the environment. Wipro also introduced a range of other products which were environment friendly and they were named as Green Ware. These products were manufactured from the materials which were free from the hazardous material such as heavy metals like lead, mercury and cadmium, polyvinyl chloride (PVC) and Brominated flame retardants. All of the other companies were using these ingredients in their products however; Wipro designed its products such as PCs without using these hazardous items. In this way, Green Ware products of the company were compliant with the Restriction of Hazardous Substances (RoHS). Wipro has been very active in joining the campaigns and initiatives taken at global level for environmental safety. Wipro joined the Green Grid in June 2008 which was a global consortium and started to enhance energy efficiency in datacenters and business computing ecosystems. The company was not joining such platforms to get aim but the aim of the company was to actually contribute in enhancing the green technology and systems. It is also evident from the fact that Wipro joined Green Grid in June 2008 and in the same month company also joined EcoEye initiative. EcoEye initiative was a comprehensive plan aimed to increase ecological sustainability in all operations and engaging its shareholders. By joining this program, Wipro showed that it is very active in taking initiatives on green concerns. As mentioned in the case study, Chandran commented on this initiative taken by Wipro. He argues that this initiative has been taken as a collaborative effort

Saturday, November 16, 2019

Minireview of A Study Essay Example for Free

Minireview of A Study Essay Synaptic transmission in vertebrate neuromuscular junctions forms the basis of this study. The communication between neurons in the nervous system occurs largely due to neurotransmitter release at the synapses. Messages on the various significant nervous system functions are coordinated through the synaptic junctions and the release of neurotransmitters. Ryanodine receptors are found in the somata of the Purkinje cells, basket cells and pre-synaptic terminals of specific synapses and terminals of basket cells. Calcium in the extracellular fluid triggers the neurotransmitter release. Now it is understood that pre-synaptic stores could participate in this same function. Ryanodine-sensitive stores of calcium also play a role. The quantum is the amount of spontaneous signals occurring in the absence of pre-synaptic action potentials and is equivalent to the release of one neurotransmitter vesicle (Katz, 1969). The action potentials are called miniature currents. For central synapses in the brain, large miniature currents are believed to arise from the release of many neurotransmitter or presynaptic vesicles and in the range of several quanta (Bekkers, 1994). Yoshida’s study (1994) revealed that these multivesicular miniature events could actually be tetrodotoxin-resistant action potentials in the pre-synaptic terminals. Other researchers have tried to explain the phenomenon from another angle, using the presence of intracellular calcium stores in the pre-synaptic terminals. Nakanishi et al localized inositol triphosphate receptors in the neural tissue of the developing and adult mouse brain (1991). These were immunolocalised in the pre-synaptic terminals of the deep cerebellar nuclei and the retina of the eyes. Narita’s studies (1998, 2000) revealed the action of ryanodine-sensitive calcium stores at the frog neuromuscular junctions. It was discovered that agents which influence the ryanodine-sensitive Calcium stores also increased the intracellular Calcium in the pre-synaptic cells and regulated acetyl choline release during high frequency stimulation. Mothet et al (1998) studied the action potentials at the pre-synaptic terminals of the buccal ganglia in Aplysia. They indicated that ryanodine inhibited while the pre-synaptic injection of Cyclic ADP Ribose augmented the action potential evoked release of acetyl choline at synapses. Studies also showed that caffeine with or without ryanodine modifies Calcium stores at the pre-synaptic terminals in autonomic ganglia (Peng, 1996; Smith et al, 1996) and in photoreceptors (Krizaj, 1999). Studies on hippocampal pyramidal cells have shown that Caffeine or thapsigargin influences the frequency of miniature IPSCs. Making an assumption, from prior studies described above, that spontaneous Calcium release from pre-synaptic Calcium stores may provide the synchronisation mechanism that causes multivesicular miniature IPSCs and the fact that such a hypothesis has not been tested systematically previously, the authors have taken up this topic for their study on cerebellar interneuron Purkinje cells. This Study   Methods Experiments were conducted on the sagittal cerebellar slices of decapitated rats aged 10-14 days of age. During the experimental recordings, the slices were perfused in saline containing prescribed concentrations of NaCl, KCl, Na H2PO4, NaHCO3, CaCl2, MgCl2 and glucose with 95:5 mixture of oxygen and carbon dioxide. Experiments were done at room temperature. For tight-seal whole-cell recordings, pipettes filled with a solution of appropriate concentrations of CsCl, MgCl2, HEPESCs, BAPTA-Cs (Molecular Probes, Eugene, Oregon), CaCl2, Na-GTP and Na-ATP and of pH 7.3 were used. Capacitance cancellation and series resistance compensation had been done. Kynurenic acid had been added to the extracellular solution to block the inotropic gluatamate receptors. TTX was present in the solution for all recordings. The calcium free solutions were prepared by leaving out Calcium and adding EGTA Na. Membrane potential was maintained at -60mV and the current was filtered at 1.5-2 kHz. Sampling was done continuously with brief interruptions. Detection and analysis were done using the IGOR-Pro programming environment. In experiments needing a Calcium channel blocker, cytochrome was added to the external solution. The toxin was prepared while the ryanodine was purchased. Testing the Calcium The Calcium in the basket cells were tested using the Two-photon laser scanning Fluorescence microscopy. For studying the action potential-evoked calcium increases, bicuculline was added to the external solution and the calcium sensitive probe Oregon Green was put into the pipettes. Scans were done and pulses were applied at the end of each 8th scan. This was repeated every minute in external solution which contained saline in order to get a baseline. The external solution was then changed to the solution containing ryanodine and recording proceeded for another 15 minutes. Another set of recordings were done with external solution not having calcium but having EGTA Na. The internal solution also had EGTA and Cs instead of K as the main cation. The responses in Spontaneous Calcium transients also were recorded using molecular probes in the external solution. A pseudo line scan was also done. For immunocytochemistry, a rabbit polyclonal anti-serum was raised to the 16 amino-acids found in all mammals. A C terminal cysteine enabled conjugation to haemocyanin. The conjugated peptide was used to immunize rabbits. Then the ELISA confirmed the specificity. The sarcoplasmic and endoplasmic reticulum microsomes derived from the skeletal muscle, cardiac tissue, whole brain and cerebellum were used for immunoblot analysis. Effects of external Calcium concentration. Large amplitude miniature IPSCs in cerebellar Purkinje cells were found sensitive to extracellular Calcium. With calcium free solution, the mIPSC frequency fell suddenly to half the control level. Continued exposure to the low level of external calcium caused the frequency of mIPSC to continue declining but at a slower rate. On washing after this, the frequency recovered and reached its initial level. The amplitude of the mIPSCs on the other hand showed a steady decline all through and no recovery on washing. With high levels of Calcium, the frequency of the mIPSCs increased rapidly and significantly. The change in amplitude varied from no response to a minimal increase. The inference was that Calcium strongly influenced mIPSCs in the Purkinje cells though frequency and amplitude were differently affected. The rapid change in frequency was interpreted as the reaction of intracellular Calcium to external Calcium changes. The slow change in amplitude was considered due to the extracellular influence on the pre-synaptic stores. The prolonged extracellular calcium removal could have caused selective elimination of large amplitude miniature IPSCs. Repeating with a calcium-free solution, many large amplitude miniature IPSCs were seen again. Then there was a sudden drop and then the amplitudes reduced to become concurrent with the control and the IPSCs were also less. The reduction seen when external Calcium was removed was not due to post-synaptic modifications. On returning to the calcium-rich solution, a slight recovery of both amplitude and frequency occurred. Paired Student’s t-tests indicate significant changes in mean amplitude and frequency between mIPSCs recorded during a 3-min control period and after 15–18 min in Calcium-free external solution. 6 sham experiments were also conducted by keeping the slices in Calcium containing external solution all throughout and these showed no obvious change. The time course of decay of the IPSCs was slower in calcium-free external solution when compared to depolarization-induced calcium transients. Effects of elevated intracellular Calcium Elevated intracellular Calcium in the Purkinje cells caused a speedy frequency reduction and a slow increase in amplitude. This sudden fall could not be explained by the intracellular calcium as BAPTA buffered the Calcium in the cells and could not have caused the IPSCs. Effect of the axons in large amplitude miniature IPSCs The immediate slow changes in the amplitude of IPSCs on withdrawal of external calcium for 3 minutes could not be attributed to the delayed removal of external calcium from pre-synaptic release sites. The effect was also not due to local Calcium influx caused by the TTX insensitive axonal depolarization. For the latter test, external Cd,   a non-selective channel blocker, was used. It reduced the action potential-evoked pre-synaptic Calcium transients seen in the axons and pre-synaptic terminals of cerebellar interneurons. The slow changes in amplitude were therefore not connected to rundown or altered post-synaptic receptors or delayed extracellular calcium removal. The only remaining explanation was that multivesicular release under the pre-synaptic calcium stores could have caused the changes in amplitude. The lack of recovery after external Calcium restoration could be due to the slow store refilling of intracellular Calcium when action potentials and subsequent calcium influx are blocked. Rise Time Kinetics The multi-vesicular release also could not completely explain the slow changes in amplitude. Rise time of IPSCs as a function of amplitude was studied after extended external calcium removal. In 6 of the 8 cells tested, the rise time was heterogenous in nature where two subpopulations were concerned. Slower decay kinetics was also noted. A faster rise time was seen in the proximal dendrites and soma. Faster IPSCs were more sensitive to external calcium removal than slow ones and these IPSCs arose at somatic synapses. The origin being multivesicular, synchronisation time must have been in the range of submillisecond. Some IPSCs had slower rise time and decays and were less sensitive to external calcium removal. These IPSCs could be arising from dendrites and could be having synchronisation of 1-4ms. Ryanodine receptors The two photon laser illumination was used to focus on the ryanodine receptors stained with a high-affinity Calcium-sensitive dye, Oregon Green BAPTA-1. Transient rises of Calcium in the stained ryanodine receptors in response to short trains of action potentials were measured. The fluorescence rises were noted. Ryanodine-sensitive Calcium stores are associated with the large amplitude mIPSCs. In the experiment Ryanodine in large concentrations of 100 ÃŽ ¼M blocked the receptors. The response recorded showed that Ryanodine reduced the mean amplitude and frequency of mIPSCs simultaneously. The responses to muscimol were not affected by ryanodine and the researchers assumed that ryanodine had no post synaptic effect. Axonal spots with calcium stores were identified in pre-synaptic terminals by recording responses to short action potentials. The intracellular Calcium fluctuations in response to differing concentrations of external calcium to which small concentrations of ryanodine were added was checked. Repeated scanning in the presence of TTX was done. Spontaneous calcium transients were noted before and after addition of ryanodine. Bright spots of fluorescence were noted at the pre-synaptic terminals. This signified the presence and increase of Calcium at the pre-synaptic terminals. Experiments were then done with small concentrations of Ryanodine 10 ÃŽ ¼M. Large amplitude mIPSCs were recorded. High frequency bursts and amplitudes of the responses were greatly increased. The bursts could reflect the response at multivesicular and monovesicular sites. The histogram comparing the amplitudes in the control and after ryanodine was added showed a significant difference. The spontaneous Calcium transients occur at basket cell axons and their frequency was increased by small concentrations of ryanodine.

Thursday, November 14, 2019

Lady Mary Wroth as Proto-Feminist Essay -- Feminism Feminist Women Cri

Lady Mary Wroth as Proto-Feminist Lady Mary Wroth is one of very few canonized woman poets in the 17th century canon (Strickland lect. Oct 11 94.). This fact alone lends a type of importance to Wroth that sets her off from her male contemporaries. Wroth wrote poems at about the same time that Robert Herrick, John Donne, Andrew Marvell, and Sir Philip Sidney (to name a few) wrote their courtly lyrics. Wroth wasn't the only woman writer from the time, instead, she was simply one of very few that were saved from historical anonymity. Lady Mary Wroth writes using a fairly conventional form of sonnet making, the "Carpe Diem" style. In using this style, she achieves an interesting internal critique of itself as poetic form. Wroth shows how the form is exclusive and at times self-defeating. Wroth exposes these faults by elaborating on images of masochistic love and how this type of love is furthered by the use of military metaphor. Lastly, I will discuss how Wroth's use of double narration and monologue format also serve to problematize the "Carpe Diem" style. "Carpe Diem" means "seize the day", and this particular translation of the phrase is of particular importance for establishing the validity of Wroth's critique. (Strickland lect. Oct 11 94). These "Carpe Diem" love sonnets usually focused around the narrator trying to seduce a woman into bed or into some type of love relationship. The need to "seize the day was worked in by the narrator in hopes of spurring the woman into action. One good example of this is in Andrew Marvell's poem "To His Coy Mistress". In this poem, Marvell writes: "And the last age should show your heart:/ ... But at my back I always hear/ Time's winged chariot hurrying near" (Marvell n.p.). Marvell... ... too well placed to be considered accidental. Although I cannot claim to be completely knowledgeable in Feminist writing I can only suppose that I have found what I think is there. WORKS CITED Adam, Robert M. & Logan, George M. ed. The Norton Anthology of English Literature: Fifth Edition. New York: W.W. Norton Co., 1986. Greer, Germaine. The Female Eunuch. New York: McGraw--Hill, 1970. Marvell, Andrew. Andrew Marvell: The Complete Poems. Elizabeth Story Donno ed. New York: Penguin, 1972. Smith, A.J. ed. John Donne: The Complete English Poems. London: Penguin, 1971. Strickland, Ronald. 17th Century English 215 (Course Packet). Normal: Pip Printing, 1994. Strickland, Ronald. Lecture. Literature of the 17th Century. Illinois State University. Normal, 11th Oct. 1994. Wroth, Lady Mary. The Poems of Lady Mary Wroth. Baton Rogue: Louisiana St. UP, 1983. Lady Mary Wroth as Proto-Feminist Essay -- Feminism Feminist Women Cri Lady Mary Wroth as Proto-Feminist Lady Mary Wroth is one of very few canonized woman poets in the 17th century canon (Strickland lect. Oct 11 94.). This fact alone lends a type of importance to Wroth that sets her off from her male contemporaries. Wroth wrote poems at about the same time that Robert Herrick, John Donne, Andrew Marvell, and Sir Philip Sidney (to name a few) wrote their courtly lyrics. Wroth wasn't the only woman writer from the time, instead, she was simply one of very few that were saved from historical anonymity. Lady Mary Wroth writes using a fairly conventional form of sonnet making, the "Carpe Diem" style. In using this style, she achieves an interesting internal critique of itself as poetic form. Wroth shows how the form is exclusive and at times self-defeating. Wroth exposes these faults by elaborating on images of masochistic love and how this type of love is furthered by the use of military metaphor. Lastly, I will discuss how Wroth's use of double narration and monologue format also serve to problematize the "Carpe Diem" style. "Carpe Diem" means "seize the day", and this particular translation of the phrase is of particular importance for establishing the validity of Wroth's critique. (Strickland lect. Oct 11 94). These "Carpe Diem" love sonnets usually focused around the narrator trying to seduce a woman into bed or into some type of love relationship. The need to "seize the day was worked in by the narrator in hopes of spurring the woman into action. One good example of this is in Andrew Marvell's poem "To His Coy Mistress". In this poem, Marvell writes: "And the last age should show your heart:/ ... But at my back I always hear/ Time's winged chariot hurrying near" (Marvell n.p.). Marvell... ... too well placed to be considered accidental. Although I cannot claim to be completely knowledgeable in Feminist writing I can only suppose that I have found what I think is there. WORKS CITED Adam, Robert M. & Logan, George M. ed. The Norton Anthology of English Literature: Fifth Edition. New York: W.W. Norton Co., 1986. Greer, Germaine. The Female Eunuch. New York: McGraw--Hill, 1970. Marvell, Andrew. Andrew Marvell: The Complete Poems. Elizabeth Story Donno ed. New York: Penguin, 1972. Smith, A.J. ed. John Donne: The Complete English Poems. London: Penguin, 1971. Strickland, Ronald. 17th Century English 215 (Course Packet). Normal: Pip Printing, 1994. Strickland, Ronald. Lecture. Literature of the 17th Century. Illinois State University. Normal, 11th Oct. 1994. Wroth, Lady Mary. The Poems of Lady Mary Wroth. Baton Rogue: Louisiana St. UP, 1983.

Monday, November 11, 2019

Leadership and Organizational Behavior Essay

A Proposal: †¢ precisely defines your research topic and the need for studying it—what is the organizational issue and OB topical area that requires attention and further study †¢ provides a research question to summarize the problem statement, however tentative it may be †¢ explains the sources critical to your proposed research, demonstrating that they are adequate for your project Proposal Organization: Your project proposal must include the following four labeled sections: Your Name (top of first page). Organization. Give the name of the organization and very briefly describe it. If you are focusing on one department in the organization – tell which one and describe it briefly. Be sure to include a description of your role in the organization. Set the context for the problem statement. Problem Statement. Identify and clearly state the problem—the leadership / management issue in which an element of the identified organization is not meeting expectations. The problem statement is usually phrased in terms of questions considerably more focused than the subject of the paper. End this section by stating the problem in the form of a question. For example, if a work group is not performing effectively, an effective problem statement might be, â€Å"How can group performance be improved?† rather than simply â€Å"Poor group performance.† A well-formed problem statement has four main characteristics: 1. Unity – the problem statement articulates a single controlling idea. The idea may be complex and have several parts, but it should be one idea nevertheless. 2. Focus – the problem should be restricted and specific enough for the reader to gain a clear idea of the OB topical area and the direction of your study and research. 3. Structure – if the problem statement is sufficiently focused, it will provide a basis for decisions about which information to include and which to exclude from the paper. 4. Interest – the problem statement should sharpen the reader’s interest in the OB topical area of interest. Research Plan. Provide an overview of what specific research/actions you will be taking on your problem statement. (surveys, journals, etc.). Do not be vague in this section. Note: Interviews are discouraged unless you secure management approval in advance. Scholarly Sources. You are required to use scholarly sources for your course project. Stay away from textbooks as your primary source. †¢ Within DeVry University Library Services (link can be found within The HUB), you have access to EBSCOhost, which offers full-text access to articles in all subject areas. Within EBSCOhost, you can do an advanced search where you have the choice to search for only â€Å"scholarly (peer reviewed) journals†. †¢ You might also consider using the Google Scholar search engine. Proposal Deadline: The proposal is due at the end of Week 2. Format of Your Proposal †¢ Header should include the title â€Å"Your Name Project Proposal† and the date †¢ Typically this is a one page document—if your need two pages, you are exceeding what is required for the proposal. †¢ Spell check / grammar check / proofread! †¢ Save your document in the following naming convention: â€Å"your last name first initial† Project Proposal.docx and leave it in the Week 2 Project Proposal Dropbox

Saturday, November 9, 2019

Frederick Douglass, Benjamin Franklin, and Ralph Waldo Emerson Essay

In our class, Survey of American Literature, we have read and analyzed the classic American works that have influenced and in some cases ingrained themselves into our country’s identity and belief system. Among those studied has been Benjamin Franklin’s Autobiography, Ralph Waldo Emerson’s essays, The American Scholar and Self -Reliance, and Frederick Douglass’ Narrative. Each of these covers a vast amount of subjects that could be discussed, but one that proves most compelling is the topic of education. These three men, who come from different life circumstances and have varied philosophies of life, each came to define the uses of education in their own ways. However, they do all seem to express the notion that education can be used to empower one’s self. In Benjamin Franklin’s Autobiography, comes through to me as a perfect example of the American dream, that being the idea that no matter where you come from, you can achieve almost anything with hard work and dedication. Coming from a lower-middle class Boston family to being one of the most famous Americans of all time is the classic rags to riches story that he himself lived out. The way he achieved this was by being self-educated. When looking at Franklin’s life, it could be said that he is a Renaissance man because he did so many things; he was a printer, a writer, an inventor, a scientist, and a statesman, and the only thing he had a formal education of was of printing. This American dream that is still deeply ingrained in our society today though, always seemed to be a bit of a myth to me. I don’t think it is right to say that if you are willing to work hard enough, you will always achieve success. Things are not that simple. Of course hard work can get you places, but some people work very hard their entire lives and still don’t achieve success due to unfair circumstances. I would say that success is achieved not only by hard work, but also by the right circumstances and a bit of luck. It seems to me that Franklin did not view education as what is important in life. What is important to him is what you accomplish in life. He talks about success and how to achieve it, and education is only part of that. â€Å"I grew convinc’d that Truth, Sincerity and Integrity in Dealings between Man and Man, were of the utmost Importance to the Felicity of Life†¦Ã¢â‚¬  pg. 268, Benjamin Franklin, The Autobiography (Part 1), The Norton Anthology of American Literature. Not that education could be seen as unimportant to him. He did create the first ever circulating library, which is a way in which others can become self-educated. He almost certainly felt that education was of great importance. It is just that I think he viewed education as a necessary means to get to the greater goal of being a successful person. Education was a way to prepare oneself for success. Ralph Waldo Emerson was a Transcendentalist, and therefore had a somewhat different take on education. He believed that all people are inherently divine. According to him, we all know truth in hearts but we often don’t recognize it or express it. I think he wants people to listen more closely to themselves for answers to their questions. Education can be used to inspire us and help us realize our truths. In The American Scholar, Emerson says the true sources of education are nature, the mind of the past (most influential being books), and the action taken of the heroic mind. In nature he believes we see a visible representation of what is in your self, and that is ultimately divine. And because true wisdom lies within, books can help bring it out. What is most interesting to me is that of taking action with the knowledge you have. I think here he relates to Franklin in the thought that an education is no good if you don’t go and use it. His definition of action: â€Å"The preamble of thought, the transition through which it passes form the unconscious to the conscious, is action. Only so much I know as I have lived†¦Ã¢â‚¬  pg. 519, Ralph Waldo Emerson, The American Scholar, The Norton Anthology of American Literature. Without action, a person would never experience the life issues that they studied. That would make it impossible to fully understand or form an  opinion over almost anything. Gaining knowledge will only be important if it is applied through action, and validated by action. Emerson sees education as way to inspire your own mind, and in turn, help you on a road of self-discovery in your own wisdom. Frederick Douglass comes from the most difficult circumstances (to put it lightly), being that he was enslaved and a black American in the 19th century. His autobiography is a story of self-discovery; he details how his growing awareness of his condition, through his self-acquired education, propelled him to re-imagine himself. He had to learn to think of himself as a human being rather than as a beast of burden, as a free man rather than as a slave. This required him to educate himself at the risk of brutal punishment and then to take the even greater risk of an escape attempt. After one failed try that could easily have cost him his life, he succeeded the second time. Douglass’ story is one of self-reliance. To him, education was necessary to his survival because it offered him a first step to get out of a life of slavery. â€Å"I understood the pathway from slavery to freedom†¦Though conscious of the difficulty of learning without a teacher, I set out with high hope, and a fixed purpose, at whatever cost of trouble, to learn how to read†¦Ã¢â‚¬  pg. 946, Frederick Douglass, Narrative, The Norton Anthology of American Literature. Each of these men, Franklin, Emerson, and Douglass, viewed the need for education for seemingly different purposes. Franklin, who focused on how to be a successful person understood that education, was an important step in preparing oneself for future accomplishments. Emerson felt we all had the answers within, but saw education as a way to prompt our understanding of those inner truths and convince us to express them. Douglass used education for survival and a small ray of hope that he would not remain a slave forever. But what is true of all these men is that education was used to better themselves, they’re understanding of the world around them, and to then educate others through their literary works. To educate the self is to empower the self.

Thursday, November 7, 2019

Frances Economy essays

Frances Economy essays A country may describe itself as having a market, command, or traditional economy when really they have a mix of all three. France is a good example of a country with all three of these economic systems. The government controls a lot of things about the economy. Many people also control parts of the economy. French people are also traditional in some of the ways that they run the economy. The French government has a major influence in the economy in France. The government retains considerable influence over key segments of the economy including the majority of the ownership of railways, electricity, aircraft, telecommunication firms, public transportation and the defense industry. This makes the French government like a command economic system where the government owns all the companies. The government also encourages economic equity by not cutting unemployment and retirement benefits which impose a heavy tax burden. This would disproportionately benefit the rich and the leaders of France are dedicated to maintain equity. This makes the government seem even more like a command system since under a command system everyone gets paid about the same amount of money and no one can get economically ahead of others. This also resembles a command economic system. However, the French government is also a lot like a market economic system. The government has been decreasing its control over a lot of sectors they once owned since the 1990s. The government is slowly selling off holdings in France Telecom, in Air France, and in the insurance and, banking. There is also private ownership of business. this resembles a market economy where there is private ownership of all the business. There is also a high unemployment rate because in market economies there is uncertainty to who does which jobs. This shows the market side of Frances economy. France also has its part of a traditional economi ...

Tuesday, November 5, 2019

A Journey of a Hundred Miles Begins with a Single Step

A Journey of a hundred miles begins with a single step It means that however long your Journey or how big and impossible the change you want to make it starts with Just one step, or action. If you have a long term goal, you cannot achieve it without taking steps or measures to achieve them. For example, I want to become a doctor. Well 10 years of school starts with English 101, and math, and science, etc Simple things sometimes lead to big things You have to start something before you can finish it.You have to write a word, then a entente, then a paragraph, then a page, then 3 more pages and you are done. Asking what it means was the first step it could mean that every step you take that step begins a new Journey! Or If you want to take a thousand miles all you have to do is take a step In a new direction! I dont know though so you might not want to use that on your paper! No matter how big the task seems, no matter how Insurmountable It seems, make a start and continue from there. Most things In life are accomplished In small stages, not In huge giant steps.Any task, broken down Into small pieces, seems much easier. It means If you never get started with anything. You never get anything done No matter how big the task or how challenging the goal, you get there by Just beginning. Without the first step, the Journey will never happen. Somebody who dreams big but never acts to make their dreams real will never attain them. But even if the dream seems unattainable, by taking that first small step, you move towards making that dream come true. In fact, the whole Journey Is made up of small steps.

Saturday, November 2, 2019

The Phenomenon of Arbitration Essay Example | Topics and Well Written Essays - 1250 words

The Phenomenon of Arbitration - Essay Example In 1931, American Congress came up with Davis-Bacon Act; the act was created for the purpose of minimum wages to be paid to those employees who are under the contracts. In 1932 Norris-LaGuardia Act was passed. The Act was created to entitle labor unions for their strikes. It also gave lots of freedom to labor unions to deal with managements. In 1933 The National Industrial Recovery Act came up with the rule of collective bargaining. This Act talked about fixed working hours of labors. In 1935 National Labor Relations Act also known as Wagner Act. In 1936 Anti-strike breaker law came into the picture. It was known as Byrnes Act. It was very effective in against of force full attempts of managements to break any labor strike. There are different workplace factors that can cause workplace fatalities. It is often being noticed that many organizations are engaged in different risk operations. Labor's day in day out put their lives under serious threats. But labors take very fewer precautions or preventive measures. Sometimes security facilities are absent in factories. It is often being noticed that old outdated technologies or machines can be very risky and dangerous. Workplace fatalities are very common but unwanted incidents. Most of the time's management negligence are towards their workers are responsible for these kinds of mishaps. Occupational Safety and Health Act has reduced the numbers of workplace fatalities. Before this act, there was no such provision to take care of workers safety and security in their workplaces.